Built in the 16th century by the Catholic Monarchs, this church is considered to be one of the finest in the city. It used to be part of the Monasterio de Santa Cruz la Real, the place where the sessions of the tribunal of the Holy Inquisition were held and where the aristocratic families of Granada were buried over the centuries.
The church is in the shape of a Latin cross with five chapels on each side. The decoration is heavily influenced by the Baroque style. The vaulted ceilings and arches are Gothic in style whilst the columns, windows, cornices, and the large door are Romanesque.
The entrance has a stone portico with three arches resting on Doric columns. They have the initials and coat of arms of the Catholic Kings carved on them, as well as the coat of arms of the Emperor Charles V, with the motto “tanto monta” in the centre.